La Fase grupal del torneo está compuesta por ocho grupos de cuatro equipos cada uno. A los octavos de final clasifican los dos mejores rendimientos de cada zona. En la fase de los 16 mejores las parejas se arman de acuerdo a la ubicación de cada uno entre todos los clasificados. El mejor clasificado, juega con el peor y así sucesivamente. Lo mismo ocurre en las siguientes rondas.
| G | Partidos | Ida | Vuelta |
| G1 | Sao Paulo |  |
vs. |  |
Atlético Mineiro | 1 - 2 | 1 - 4 |
| G2 | Tijuana |  |
vs. |  |
Palmeiras | 0 - 0 | 1 - 2 |
| G3 | Newell's Old Boys |  |
vs. |  |
Vélez Sarsfield | 0 - 1 | 1 - 2 |
| G4 | Boca Juniors |  |
vs. |  |
Corinthians | 1 - 0 | 1 - 1 |
| G5 | Emelec |  |
vs. |  |
Fluminense | 2 - 1 | 0 - 2 |
| G6 | Tigre |  |
vs. |  |
Olimpia | 2 - 1 | 0 - 2 |
| G7 | Real Garcilaso |  |
vs. |  |
Nacional | 1 - 0 | 0-1 (4-1) |
| G8 | Gremio |  |
vs. |  |
Ind. Santa Fe | 2 - 1 | 0 - 1 |
| G | Partidos | Ida | Vuelta |
| G9 | Atl. Mineiro | |
vs. | |
Tijuana | 2 - 2 | 1 - 1 |
| G10 | Newell's Old Boys | |
vs. | |
Boca Juniors | 0 - 0 | 0-0 (10-9) |
| G11 | Real Garcilaso | |
vs. | |
Ind Santa Fe | 1 - 3 | 0 - 2 |
| G12 | Fluminense | |
vs. | |
Olimpia | 0 - 0 | 1 - 2 |
| G | Partidos | Ida | Vuelta |
| G13 | Atl. Mineiro | |
vs. | |
Newell's Old Boys | 0 - 2 | 10-06 |
| G14 | Ind Santa Fe | |
vs. | |
Olimpia | 0 - 2 | 10-06 |
| G | Partidos | Ida | Vuelta |
| G15 | Atl. Mineiro | |
vs. | |
Olimpia | 17/07 | 24/07 |
| G | Partidos | Ida | Vuelta |
| G1 | Tigre | |
vs. |  |
Deportivo Anzoátegui | 2 - 1 | 3 - 0 |
| G2 | Liga de Quito |  |
vs. | |
Gremio | 1 - 0 | 0 - 1 (4 - 5) |
| G3 | Deportes Tolima |  |
vs. |  |
Universidad César Vallejo | 1 - 0 | 2 - 1 |
| G4 | Defensor Sporting |  |
vs. | |
Olimpia | 0 - 0 | 0 - 2 |
| G5 | Sao Paulo | |
vs. |  |
Boliviar | 5 - 0 | 3 - 4 |
| G6 | Club León |  |
vs. |  |
Deportes Iquique | 1 - 1 | 1 - 1 (2 - 4) |
| Grupo 1 | PTS | PJ | PG | PE | PP | GF | GC | +/- |
| 1. | |
Nacional | 10 | 6 | 3 | 1 | 2 | 10 | 6 | 4 |
| 2. | |
Boca Juniors | 9 | 6 | 3 | 0 | 3 | 7 | 7 | 0 |
| 3. |  |
Toluca | 8 | 6 | 2 | 2 | 2 | 8 | 11 | -3 |
| 4. |  |
Barcelona | 6 | 6 | 1 | 3 | 2 | 5 | 6 | -1 |
| Local | Visitante | Fecha - Hora | Ciudad |
| Nacional | |
2 - 2 | |
Barcelona | 12/02 | Montevideo |
| Boca Juniors | |
1 - 2 | |
Toluca | 13/02 | Buenos Aires |
| Toluca | |
2 - 3 | |
Nacional | 19/02 | Toluca |
| Barcelona | |
0 - 2 | |
Boca Juniors | 27/02 | Guayaquil |
| Toluca | |
1 - 1 | |
Barcelona | 06/03 | Toluca |
| Boca Juniors | |
0 - 1 | |
Nacional | 07/03 | Buenos Aires |
| Barcelona | |
0-0 | |
Toluca | 13/03 | Guayaquil |
| Nacional | |
0-1 | |
Boca Juniors | 14/03 | Montevideo |
| Boca Juniors | |
1 - 0 | |
Barcelona | 03/04 | Buenos Aires |
| Nacional | |
4 - 0 | |
Toluca | 04/04 | Montevideo |
| Barcelona | |
1 - 0 | |
Nacional | 17/04 | Guayaquil |
| Toluca | |
3 - 2 | |
Boca Juniors | 17/04 | Toluca |
| Grupo 2 | PTS | PJ | PG | PE | PP | GF | GC | +/- |
| 1. | |
Palmeiras | 9 | 6 | 3 | 0 | 3 | 5 | 5 | 0 |
| 2. | |
Tigre | 9 | 6 | 3 | 0 | 3 | 9 | 10 | -1 |
| 3. |  |
Libertad | 8 | 6 | 2 | 2 | 2 | 10 | 8 | 2 |
| 4. |  |
Sporting Cristal | 8 | 6 | 2 | 2 | 2 | 8 | 8 | 0 |
| Local | Visitante | Fecha - Hora | Ciudad |
| Palmeiras | |
2 - 1 | |
Sporting Cristal | 14/02 | San Pablo |
| Tigre | |
0 - 2 | |
Libertad | 21/02 | Victoria |
| Sporting Cristal | |
2 - 0 | |
Tigre | 28/02 | Lima |
| Libertad | |
2 - 0 | |
Palmeiras | 28/02 | Asunción |
| Libertad | |
2 - 2 | |
Sporting Cristal | 06/03 | Asunción |
| Tigre | |
1 - 0 | |
Palmeiras | 06/03 | Victoria |
| Sporting Cristal | |
1 - 1 | |
Libertad | 12/03 | Lima |
| Palmeiras | |
2 - 0 | |
Tigre | 02/04 | San Pablo |
| Tigre | |
3 - 1 | |
Sporting Cristal | 09/04 | Victoria |
| Palmeiras | |
1 - 0 | |
Libertad | 11/04 | San Pablo |
| Sporting Cristal | |
1 - 0 | |
Palmeiras | 18/04 | Lima |
| Libertad | |
3 - 5 | |
Tigre | 18/04 | Asunción |
| Grupo 3 | PTS | PJ | PG | PE | PP | GF | GC | +/- |
| 1. | |
Atlético Mineiro | 15 | 6 | 5 | 0 | 1 | 16 | 9 | 7 |
| 2. | |
Sao Paulo | 7 | 6 | 2 | 1 | 2 | 8 | 8 | 0 |
| 3. |  |
Arsenal | 7 | 6 | 2 | 1 | 2 | 10 | 15 | -5 |
| 4. |  |
The Strongest | 6 | 6 | 2 | 0 | 4 | 7 | 8 | -1 |
| Local | Visitante | Fecha - Hora | Ciudad |
| Atlético Mineiro | |
2 - 1 | |
Sao Paulo | 13/02 | Belo Horizonte |
| The Strongest | |
2 - 1 | |
Arsenal | 14/02 | La Paz |
| Arsenal | |
2 - 5 | |
Atlético Mineiro | 26/02 | Sarandí |
| Sao Paulo | |
2 - 1 | |
The Strongest | 28/02 | San Pablo |
| Sao Paulo | |
1 - 1 | |
Arsenal | 07/03 | San Pablo |
| Atlético Mineiro | |
2 - 1 | |
The Strongest | 08/03 | Belo Horizonte |
| The Strongest | |
1 - 2 | |
Atlético Mineiro | 13/03 | La Paz |
| Arsenal | |
2 - 1 | |
Sao Paulo | 14/03 | Sarandí |
| Atlético Mineiro | |
5 - 2 | |
Arsenal | 03/04 | Belo Horizonte |
| The Strongest | |
2 - 1 | |
Sao Paulo | 04/04 | La Paz |
| Arsenal | |
2 - 1 | |
The Strongest | 17/04 | Sarandí |
| Sao Paulo | |
2 - 0 | |
Atlético Mineiro | 17/04 | San Pablo |
| Grupo 4 | PTS | PJ | PG | PE | PP | GF | GC | +/- |
| 1. | |
Vélez | 13 | 6 | 4 | 1 | 1 | 10 | 3 | 7 |
| 2. | |
Emelec | 10 | 6 | 3 | 1 | 2 | 5 | 4 | 1 |
| 3. |  |
Peñarol | 9 | 6 | 3 | 0 | 3 | 7 | 7 | 0 |
| 4. | |
Deportes Iquique | 3 | 6 | 1 | 0 | 5 | 5 | 13 | -8 |
| Local | Visitante | Fecha - Hora | Ciudad |
| Deportes Iquique | |
1 - 2 | |
Peñarol | 12/02 | Iquique |
| Emelec | |
1 - 0 | |
Vélez | 12/02 | Guayaquil |
| Peñarol | |
1 - 0 | |
Emelec | 19/02 | Montevideo |
| Vélez | |
3 - 0 | |
Deportes Iquique | 20/03 | Buenos Aires |
| Peñarol | |
0 - 1 | |
Vélez | 26/03 | Montevideo |
| Deportes Iquique | |
2 - 0 | |
Emelec | 27/03 | Iquique |
| Emelec | |
2 - 1 | |
Deportes Iquique | 05/03 | Guayaquil |
| Vélez | |
3 - 1 | |
Peñarol | 12/03 | Buenos Aires |
| Emelec | |
2 - 0 | |
Peñarol | 02/04 | Guayaquil |
| Deportes Iquique | |
1 - 3 | |
Vélez | 02/04 | Iquique |
| Vélez | |
0 - 0 | |
Emelec | 09/04 | Buenos Aires |
| Peñarol | |
3 - 0 | |
Deportes Iquique | 09/04 | Montevideo |
| Grupo 5 | PTS | PJ | PG | PE | PP | GF | GC | +/- |
| 1. | |
Corinthians | 13 | 6 | 4 | 1 | 1 | 10 | 2 | 8 |
| 2. | |
Tijuana | 13 | 6 | 4 | 1 | 1 | 8 | 4 | 4 |
| 3. |  |
San José | 5 | 6 | 1 | 2 | 3 | 5 | 11 | -6 |
| 4. |  |
Millonarios | 3 | 6 | 1 | 0 | 5 | 2 | 8 | -6 |
| Local | Visitante | Fecha - Hora | Ciudad |
| Millonarios | |
0 - 1 | |
Tijuana | 19/02 | Bogotá |
| San José | |
1 - 1 | |
Corinthians | 20/02 | Oruro |
| Tijuana | |
4 - 0 | |
San José | 26/02 | Tijuana |
| Corinthians | |
2 - 0 | |
Millonarios | 27/02 | San Pablo |
| Tijuana | |
1 - 0 | |
Corinthians | 06/03 | Tijuana |
| Millonarios | |
2 - 1 | |
San José | 07/03 | Bogotá |
| Corinthians | |
3 - 0 | |
Tijuana | 13/03 | San Pablo |
| San José | |
2 - 0 | |
Millonarios | 14/03 | Oruro |
| Millonarios | |
0 - 1 | |
Corinthians | 03/04 | Bogotá |
| San José | |
1 - 1 | |
Tijuana | 03/04 | Oruro |
| Corinthians | |
3 - 0 | |
San José | 10/04 | San Pablo |
| Tijuana | |
1 - 0 | |
Millonarios | 10/04 | Tijuana |
| Grupo 6 | PTS | PJ | PG | PE | PP | GF | GC | +/- |
| 1. | |
Santa Fe | 14 | 6 | 4 | 2 | 0 | 9 | 4 | 5 |
| 2. | |
Real Garcilaso | 10 | 6 | 3 | 1 | 2 | 8 | 7 | 1 |
| 3. | |
Deportes Tolima | 8 | 6 | 2 | 2 | 2 | 7 | 5 | 2 |
| 4. |  |
Cerro Porteño | 1 | 6 | 0 | 1 | 5 | 3 | 11 | -8 |
| Local | Visitante | Fecha - Hora | Ciudad |
| Real Garcilaso | |
1 - 1 | |
Santa Fe | 13/02 | Cuzco |
| Deportes Tolima | |
2 - 1 | |
Cerro Porteño | 14/02 | Ibagué |
| Santa Fe | |
1 - 1 | |
Deportes Tolima | 21/02 | Bogotá |
| Cerro Porteño | |
0 - 1 | |
Real Garcilaso | 21/02 | Asunción |
| Deportes Tolima | |
0 - 1 | |
Real Garcilaso | 26/02 | Ibagué |
| Cerro Porteño | |
1 - 2 | |
Santa Fe | 07/03 | Asunción |
| Santa Fe | |
1 - 0 | |
Cerro Porteño | 02/04 | Bogotá |
| Real Garcilaso | |
0 - 3 | |
Deportes Tolima | 02/04 | Cuzco |
| Deportes Tolima | |
1 - 2 | |
Santa Fe | 09/04 | Ibagué |
| Real Garcilaso | |
5 - 1 | |
Cerro Porteño | 10/04 | Cuzco |
| Santa Fe | |
2 - 0 | |
Real Garcilaso | 16/04 | Bogotá |
| Cerro Porteño | |
0 - 0 | |
Deportes Tolima | 16/04 | Asunción |
| Grupo 7 | PTS | PJ | PG | PE | PP | GF | GC | +/- |
| 1. | |
Olimpia | 13 | 6 | 4 | 1 | 1 | 16 | 7 | 10 |
| 2. | |
Newell's Old Boys | 9 | 6 | 3 | 0 | 3 | 11 | 10 | 1 |
| 3. |  |
Universidad de Chile | 9 | 6 | 3 | 0 | 3 | 7 | 9 | -2 |
| 4. |  |
Deportivo Lara | 4 | 6 | 1 | 1 | 4 | 8 | 16 | -8 |
| Local | Visitante | Fecha - Hora | Ciudad |
| Universidad de Chile | |
2 - 0 | |
Deportivo Lara | 12/02 | Santiago |
| Newell's Old Boys | |
3 - 1 | |
Olimpia | 14/02 | Rosario |
| Olimpia | |
3 - 0 | |
Universidad de Chile | 19/02 | Asunción |
| Deportivo Lara | |
1 - 2 | |
Newell's Old Boys | 21/02 | Cabudare |
| Olimpia | |
2 - 2 | |
Deportivo Lara | 05/03 | Asunción |
| Newell's Old Boys | |
1 - 2 | |
Universidad de Chile | 05/03 | Rosario |
| Universidad de Chile | |
0 - 2 | |
Newell's Old Boys | 12/03 | Santiago |
| Deportivo Lara | |
1 - 5 | |
Olimpia | 13/03 | Cabudare |
| Universidad de Chile | |
0 - 1 | |
Olimpia | 02/04 | Santiago |
| Newell's Old Boys | |
3 - 1 | |
Deportivo Lara | 04/04 | Rosario |
| Deportivo Lara | |
2 - 3 | |
Universidad de Chile | 11/04 | Cabudare |
| Olimpia | |
4 - 1 | |
Newell's Old Boys | 11/04 | Asunción |
| Grupo 8 | PTS | PJ | PG | PE | PP | GF | GC | +/- |
| 1. | |
Fluminense | 10 | 6 | 3 | 1 | 2 | 10 | 5 | 5 |
| 2. | |
Gremio | 8 | 6 | 2 | 2 | 2 | 10 | 6 | 4 |
| 3. |  |
Huachipato | 8 | 6 | 2 | 2 | 2 | 10 | 8 | 2 |
| 4. |  |
Caracas | 6 | 6 | 2 | 0 | 4 | 6 | 12 | -6 |
| Local | Visitante | Fecha | Ciudad |
| Caracas | |
0 - 1 | |
Fluminense | 13/02 | Caracas |
| Gremio | |
1 - 2 | |
Huachipato | 14/02 | Porto Alegre |
| Fluminense | |
0 - 3 | |
Gremio | 20/02 | Rio de Janeiro |
| Huachipato | |
1 - 3 | |
Caracas | 20/02 | Talcahuano |
| Huachipato | |
1 - 2 | |
Fluminense | 27/02 | Talcahuano |
| Gremio | |
4 - 1 | |
Caracas | 05/03 | Porto Alegre |
| Fluminense | |
1 - 1 | |
Huachipato | 06/03 | Rio de Janeiro |
| Caracas | |
2 - 1 | |
Gremio | 12/03 | Caracas |
| Caracas | |
0 - 4 | |
Huachipato | 04/04 | Caracas |
| Gremio | |
0 - 0 | |
Fluminense | 10/04 | Porto Alegre |
| Fluminense | |
1 - 0 | |
Caracas | 18/04 | Rio de Janeiro |
| Huachipato | |
1 - 1 | |
Gremio | 18/04 | Talcahuano |
